NERLYNX therapy and a common side effect

Nerlynx can cause diarrhoea when therapy is commenced. Diarrhoea may be severe, causing dehydration, unless loperamide is introduced to prevent or reduce this side effect. Patients are advised to speak to their clinicians if they can’t take loperamide and to start taking loperamide with the first dose. Professor Arlene Chan discusses this side effect and optimal management.